USP7/MAGED1-MEDIATED H2A MONOUBIQUITINATION IN THE PARAVENTRICULAR THALAMUS: AN EPIGENETIC MECHANISM INVOLVED IN COPYRIGHT USE DISORDER

USP7/Maged1-mediated H2A monoubiquitination in the paraventricular thalamus: an epigenetic mechanism involved in copyright use disorder

Abstract The risk of developing drug addiction is strongly influenced by the epigenetic landscape and chromatin remodeling.While histone modifications such as methylation and acetylation have been studied in the ventral tegmental area and nucleus accumbens (NAc), the role of H2A monoubiquitination remains unknown.Our investigations, initially focus

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Non-coding RNAs change their expression profile after Retinoid induced differentiation of the promyelocytic cell line NB4

Abstract Background The importance of non-coding RNAs (ncRNAs) as fine regulators of eukaryotic gene expression has emerged by several studies focusing on microRNAs (miRNAs).miRNAs represent a newly discovered family of non coding-RNAs.They are thought to be crucial players of human hematopoiesis and related tumorigenesis and to represent a potenti

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